The production of chemical active pharmaceutical ingredients (chem APIs) involves a variety of process steps that must be optimally coordinated.
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The process chemistry group at Boehringer-Ingelheim, for example, targets a VTO of less than 1 for any given synthetic step or chemical process. Additionally, the raw conversion cost of an API synthesis (in dollars per batch) can be calculated from the VTO, given the operating cost and usable capacity of a particular reactor.
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Figure 79.2 Manufacturing process in the pharmaceutical industry. ... Chemical synthesis processes use ... A schematic diagram of an organic synthesis process is ...
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ijerph-10-01231-f001: Schematic diagram of the HiPco synthesis process
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Few decisions in pharmaceutical operations are as critical as selecting the right API Development process. CordenPharma’s chemical development scientists have the skill and experience to meet a wide range of outsourcing needs from the custom synthesis and scale-up of an existing route, to identification and development of new …